An Emergency Medicine Broadsheet
·Phoenix·
Est. MMXXVI
Blue Fish Med · Today's Topic
Nasal Bone Fractures
Most isolated nasal fractures need clinical diagnosis and outpatient care, but an unrecognized septal hematoma can cause cartilage necrosis, saddle-nose deformity, and infection. The dangerous question is not “Is the bone broken?” but “Is the septum compromised, and is the airway threatened?”
A 24-year-old man arrives after colliding face-first with another player during a basketball game. Blood darkens the gauze beneath his nose, and the bridge looks newly crooked; each breath produces a faint whistle through the left nostril. He insists he can breathe “well enough” and denies losing consciousness, but his friend says the nose looked different immediately after impact. You lift the tip of the nose to inspect the septum, and the next decision is still pending.
— What’s your move? Read on.
Before you read
Which nasal injury requires urgent drainage?
When is imaging unnecessary, and when does the patient need specialty follow-up?
When to Think of It
Nasal deformity, tenderness, epistaxis, swelling, crepitus, obstruction, or periorbital ecchymosis after blunt facial trauma. Always consider associated orbital, naso-orbito-ethmoid, maxillary, skull-base, and cervical injuries.
Sick or Not Sick
Sick vs. not sick: Is there an airway-threatening or time-sensitive associated injury? Look specifically for septal hematoma, uncontrolled hemorrhage, CSF rhinorrhea, open fracture, severe deformity, malocclusion, ocular injury, facial instability, or altered mental status.
The First Fifteen Minutes
Sit the patient forward and apply firm, continuous pressure to the soft nasal alae for 10–15 minutes; this is the fastest mechanical control of anterior epistaxis.
Ongoing anterior bleeding → oxymetazoline 0.05% nasal spray, 2 sprays per nostril, then repeat pressure; vasoconstriction shrinks mucosal vessels. Avoid or use cautiously in severe uncontrolled hypertension or significant ischemic disease.
Pain without major bleeding → acetaminophen 1,000 mg PO; it provides analgesia without impairing platelet function. If pain is severe and bleeding is controlled → fentanyl 25–50 mcg IV, titrated every 5 minutes, because rapid opioid analgesia facilitates examination; monitor ventilation.
Visible septal hematoma → urgent ENT consultation for incision and drainage; do not merely prescribe medication, because trapped blood threatens septal cartilage.
Suspected open or grossly contaminated fracture → cefazolin 2 g IV once, because it provides early skin-flora coverage while definitive evaluation occurs; antibiotic choice and duration should follow local facial-trauma protocol.
Tetanus status incomplete or unknown with a contaminated/open wound → tetanus toxoid-containing vaccine 0.5 mL IM; add tetanus immune globulin 250 IU IM when the wound is dirty and the patient has an incomplete/unknown primary series, because passive antitoxin is needed before active immunity develops.
Definitive Care & Disposition
No routine imaging is needed for an uncomplicated isolated nasal fracture; plain films rarely change care. CT maxillofacial imaging is appropriate for suspected complex facial fracture, significant mechanism, ocular findings, malocclusion, facial instability, or concerning neurologic findings. Reassess after swelling improves; displaced deformity or persistent obstruction generally needs closed reduction by ENT/plastics, often within 7–14 days in adults. Septal hematoma, CSF leak, open/complex fracture, uncontrolled epistaxis, or associated injuries warrant urgent specialty evaluation or admission. Discharge uncomplicated injuries with elevation, cold packs, analgesia, sinus precautions when indicated, and follow-up.
How This One Kills
The lethal-to-function failure is missing a septal hematoma: the patient may have little external deformity, but bilateral or unilateral boggy septal swelling progressively devascularizes cartilage and later produces saddle-nose deformity or abscess.
The Differential — What Else Looks Like This
Septal hematoma — fluctuant, boggy swelling of the septum that does not shrink with topical vasoconstrictor; confusing it with congestion causes cartilage loss.
Naso-orbito-ethmoid fracture — telecanthus, medial canthal tendon laxity, or CSF rhinorrhea; treating it as an isolated nasal fracture misses major midface injury.
Le Fort fracture — mobile maxilla or malocclusion; missed instability can compromise airway and require operative fixation.
Simple epistaxis without fracture — bleeding but no new deformity, tenderness, or instability; unnecessary imaging and reduction add harm without benefit.
The Second-Day Story
In older adults, anticoagulated patients, and patients presenting hours after injury, swelling and bruising may obscure the deformity while pain is muted. In children, the cartilage injury may be more important than radiographically visible bone injury. A careful intranasal examination—looking for septal asymmetry, fluctuation, obstruction, and clear drainage—plus assessment of occlusion and ocular findings catches the clinically important injury even when the nose looks only mildly swollen.
Back to Our Patient
Back to the 24-year-old basketball player: he has a new mild dorsal deformity and tenderness but no malocclusion, ocular abnormality, CSF-like drainage, facial instability, or septal swelling; bleeding stops with pressure and oxymetazoline. He is therefore not sick from an airway-threatening associated injury, and the likely problem is an isolated displaced nasal fracture. After analgesia and a complete intranasal examination, he is discharged without routine imaging, with cold packs, return precautions for obstruction or recurrent bleeding, and ENT/plastics follow-up for reassessment and possible reduction after swelling decreases.
Patient Presentation to Attending
How you’d present this patient on the floor — tight, pertinent positives and negatives, no rambling
“This is a 24-year-old man with blunt nasal trauma during basketball, presenting with epistaxis, pain, left-sided obstruction, and a new dorsal deviation. He has no loss of consciousness, vomiting, malocclusion, diplopia, vision loss, facial instability, or clear rhinorrhea. His bleeding stopped with pressure and topical vasoconstrictor; exam shows localized nasal tenderness and deformity but no septal hematoma, ocular injury, or other midface instability. He is hemodynamically stable and neurologically intact. My assessment is an isolated displaced nasal fracture without an emergent complication, so I plan analgesia, no routine imaging, discharge precautions, and ENT follow-up for reassessment and possible reduction.”
Study Directive
Practice a trauma nose examination: external deformity, septum, occlusion, ocular motility, visual acuity, and CSF-leak screen.
Review photographs or diagrams of septal hematoma, NOE fracture, and Le Fort fractures; identify the discriminating finding for each.
Write a discharge plan for isolated nasal fracture and a separate escalation plan for septal hematoma.
Complete 10 facial-trauma questions and explain why CT is or is not indicated in each.
Hassankhani A, Amoukhteh M, Jannatdoust P, et al. · Emerg Radiol, 2024 · PMID 38538882 · cited 1×
Pediatric nasal ultrasonography can provide a radiation-free adjunct when the examination is equivocal, but urgent bedside assessment for deformity and septal hematoma remains essential.
Tranexamic acid can reduce death from traumatic hemorrhage when given early to selected patients, but it is not a universal hemostatic. “Give TXA to...
A 32-year-old woman lies on the trauma bay stretcher after a high-speed crash, her jeans soaked through at the right thigh. Her skin is cool and gray, and the monitor shows a heart rate of 132 with a narrowing pulse pressure. A nurse asks whether the familiar antifibrinolytic should be drawn up while the team searches for the source of blood loss. The answer depends on a clock, a physiology threshold, and whether this is actually the kind of bleeding the drug helps.
Before You Read
Which bleeding patient benefits from TXA, and how early must it be given?
When does TXA become inappropriate or potentially harmful?
What definitive intervention must never be delayed for the drug?
Why It Matters
Tranexamic acid can reduce death from traumatic hemorrhage when given early to selected patients, but it is not a universal hemostatic. “Give TXA to everything” risks distracting from compression, blood products, surgery, and interventional radiology—and may cause harm when used late or without a bleeding indication.
When to Think of It
Suspected or confirmed major traumatic hemorrhage with shock, ongoing bleeding, or a high likelihood of massive transfusion, especially within 3 hours of injury. It may also be considered in selected postpartum hemorrhage and some mucosal bleeding protocols, but evidence and dosing differ by indication.
Sick or Not Sick
Sick vs. not sick: Is this clinically significant hemorrhage occurring within the evidence-supported treatment window? TXA is an adjunct for bleeding—not a treatment for isolated anemia, minor wounds, routine epistaxis, GI bleeding without a local protocol, or every trauma patient.
The First Fifteen Minutes
Major traumatic hemorrhage and injury <3 hours → tranexamic acid 1 g IV infused over 10 minutes, followed by 1 g IV over 8 hours; it inhibits plasminogen activation and stabilizes formed clot. Confirm local massive-transfusion protocol, especially with uncertain timing.
Do not give TXA when there is no significant bleeding, when injury occurred >3 hours ago, or when the indication is unclear; late administration in trauma may be ineffective or harmful.
Ongoing external bleeding → direct pressure, wound packing, or tourniquet immediately; a tourniquet placed proximal to life-threatening limb bleeding stops flow mechanically, whereas TXA cannot replace source control.
Hemorrhagic shock → activate a massive transfusion protocol and give balanced blood products per local protocol; blood restores oxygen-carrying capacity and coagulation factors, which TXA alone cannot do.
Suspected tension pneumothorax or tamponade → immediate decompression or pericardial intervention as indicated; correcting mechanical causes of shock takes priority over antifibrinolysis.
If using TXA for postpartum hemorrhage rather than trauma → 1 g IV over 10 minutes within 3 hours of birth, repeat 1 g IV once if bleeding continues after 30 minutes or restarts within 24 hours; follow obstetric protocol because this is a separate evidence base.
Definitive Care & Disposition
Perform hemorrhage control: operative exploration, pelvic stabilization/embolization, endoscopy, uterine management, or interventional radiology as appropriate. Continue transfusion guided by physiology, point-of-care testing, and local protocol; correct hypothermia, hypocalcemia, acidosis, and coagulopathy. TXA is not a substitute for fibrinogen replacement, calcium, plasma, platelets, or source control. Patients receiving TXA for major hemorrhage require trauma-center admission, usually ICU or operating room/interventional radiology depending on the source.
How This One Kills
The feared error is giving TXA while delaying definitive hemorrhage control—especially a tourniquet, laparotomy, pelvic hemorrhage control, or blood transfusion—because the medication creates false reassurance while exsanguination continues.
The Atypical Presentation
Older adults, pregnant patients, beta-blocked patients, and those with early compensated shock may have a deceptively normal heart rate or blood pressure. Conversely, a dramatic mechanism may produce little actual hemorrhage. Use mental status, skin perfusion, pulse pressure, shock index, serial examination, ultrasound, lactate/base deficit, and observed blood loss rather than mechanism or one vital sign alone; establish the injury time before deciding on TXA.
Back to Our Patient
Back to the 32-year-old woman: her cool skin, tachycardia, narrowing pulse pressure, soaked clothing, and recent crash identify clinically significant traumatic hemorrhage within the treatment window. While a tourniquet is applied to the thigh and the massive transfusion protocol begins, she receives TXA 1 g IV over 10 minutes followed by the protocol infusion because it may stabilize clot while resuscitation proceeds. Ultrasound and examination suggest ongoing extremity hemorrhage, so definitive operative vascular control—not TXA alone—is required; she goes directly to the operating room after initial blood-product resuscitation.
Patient Presentation to Attending
“This is a 32-year-old woman after a high-speed MVC with ongoing right-thigh hemorrhage and signs of hemorrhagic shock, including heart rate 132, cool mottled skin, and narrowing pulse pressure. She has no evidence yet of tension physiology, and the injury occurred approximately 45 minutes ago. A proximal tourniquet is being applied, large-bore access is established, and the massive transfusion protocol is active. Given significant traumatic bleeding within 3 hours, I recommend TXA 1 g IV over 10 minutes followed by 1 g over 8 hours, without delaying operative hemorrhage control. She needs immediate trauma surgery evaluation and operating-room disposition.”
Study Directive
Memorize the trauma TXA timing and dosing regimen, then write it from memory in 30 seconds.
Build a one-page “TXA yes/no” algorithm using bleeding severity, injury time, and indication.
Compare trauma and postpartum TXA indications and doses using current institutional protocols.
Complete 10 hemorrhagic-shock cases and identify the intervention that must precede or accompany TXA.
Key Medications
Tranexamic acid for major trauma within 3 hours: 1 g IV over 10 minutes, then 1 g IV over 8 hours. Some protocols use weight-based regimens; check Lexicomp, UpToDate, or institutional trauma protocol if the indication, timing, renal function, or repeat dosing is uncertain.
Tranexamic acid for postpartum hemorrhage: 1 g IV over 10 minutes, repeat 1 g once if indicated; use obstetric protocol.
Do not give TXA by rapid IV push; hypotension can occur.
Renal impairment requires dose adjustment; check a reference.
Pediatric trauma dosing is protocol-specific and weight-based; do not use the adult 1-g regimen automatically.
High-Yield Pearls
The treatment window is central: early trauma TXA is not a “better late than never” medication.
A tourniquet, operation, embolization, and blood products treat the cause and consequences of hemorrhage; TXA only modifies fibrinolysis.
Do not let a dramatic mechanism substitute for evidence of clinically important bleeding.
The Mimics
Trauma without major hemorrhage — stable vital signs and no ongoing blood loss; TXA adds treatment without demonstrated benefit.
Disseminated intravascular coagulation — diffuse bleeding with systemic illness and abnormal coagulation; antifibrinolysis alone may worsen unaddressed microvascular thrombosis.
Isolated chronic anemia — low hemoglobin without acute blood loss or shock; TXA does not restore oxygen delivery.
Board Question
A patient with blunt polytrauma has ongoing hemorrhage and arrives 90 minutes after injury. Which TXA strategy is best supported?
A1 g IV only after definitive surgery
B1 g IV over 10 minutes followed by 1 g over 8 hours
C2 g rapid IV push regardless of blood pressure
DTXA only after thromboelastography confirms hyperfibrinolysis
Reveal answer
Correct: B
Early TXA in major traumatic hemorrhage is given as a 1-g loading dose followed by 1 g over 8 hours in the commonly used CRASH-2 regimen. It must accompany, not delay, blood resuscitation and definitive source control.
Use this multisociety guideline for practical trauma TXA recommendations, including patient selection, early administration, dosing, and prehospital-to-hospital protocols.
Blast injuries combine pressure, fragments, blunt displacement, burns, inhalational injury, and crush complications. A normal initial examination can...
0:00 / –:––AI‑generated audio
The Case
A 37-year-old construction worker is carried from a warehouse explosion with soot around his lips and ringing in both ears. His jacket is torn, but there is no obvious penetrating wound; he is awake, anxious, and breathing faster than the monitor’s oxygen saturation would suggest. Several co-workers are arriving behind him, some walking and some silent. The first examination must account for injuries that are invisible at the door.
Before You Read
What are the four injury mechanisms created by an explosion?
Which apparently stable blast patient needs prolonged observation?
What finding changes the airway plan before swelling worsens?
Why It Matters
Blast injuries combine pressure, fragments, blunt displacement, burns, inhalational injury, and crush complications. A normal initial examination can deteriorate as pulmonary barotrauma, airway edema, occult hemorrhage, or compartment injury declares itself.
When to Think of It
Ask about distance, enclosure, water exposure, primary blast wave, falling debris, fire, and duration of entrapment. Look for tympanic membrane rupture, respiratory distress, hypoxia, hemoptysis, chest pain, abdominal pain, penetrating wounds, burns, amputation, neurologic symptoms, and crush injury.
Sick or Not Sick
Sick vs. not sick: Does the patient have threatened airway, respiratory failure, shock, major burn, traumatic brain injury, or suspected internal injury? Immediate threats are airway obstruction, tension pneumothorax, massive hemorrhage, and blast lung.
The First Fifteen Minutes
Hypoxemia or respiratory distress → oxygen by the device needed to maintain adequate oxygenation; oxygen treats hypoxemia but does not reverse blast lung.
Suspected tension pneumothorax with shock or severe respiratory compromise → immediate needle/finger decompression followed by chest tube; do not wait for imaging because pressure physiology kills before the radiograph.
Major traumatic hemorrhage → activate massive transfusion and give blood products per local protocol; restore oxygen delivery and coagulation while searching for the source.
Major traumatic hemorrhage within 3 hours → TXA 1 g IV over 10 minutes, then 1 g IV over 8 hours; it stabilizes clot but does not replace hemorrhage control. Verify institutional trauma protocol.
Severe pain → fentanyl 25–50 mcg IV, titrated every 5 minutes; it provides rapid analgesia, but reassess ventilation frequently in blast-lung patients.
Open, contaminated wound → cefazolin 2 g IV once, with broader or anaerobic coverage guided by contamination and local protocol; early antibiotics reduce bacterial inoculation complications.
Unknown or incomplete tetanus protection with contaminated wounds → tetanus vaccine 0.5 mL IM; add tetanus immune globulin 250 IU IM when primary immunization is incomplete or unknown and the wound is dirty.
Severe agitation or inability to protect the airway with suspected inhalation injury → prepare early RSI; etomidate 0.3 mg/kg IV for induction and rocuronium 1.2 mg/kg IV for paralysis are common options, because securing an airway before edema progresses is safer than rescue intubation. Doses vary with physiology; confirm the institutional RSI protocol.
Definitive Care & Disposition
Perform ATLS evaluation, serial respiratory examinations, chest imaging, eFAST, and targeted CT when stable. Observe patients with significant blast exposure, respiratory symptoms, abnormal chest imaging, hypoxia, hemoptysis, or enclosed-space exposure even if initially stable; delayed pulmonary deterioration may occur. Admit blast lung, significant burns, inhalational injury, major wounds, neurologic injury, abdominal injury, crush syndrome, or persistent symptoms to a trauma/burn center, often ICU. Evaluate for rhabdomyolysis, hyperkalemia, compartment syndrome, and renal failure after entrapment.
How This One Kills
The classic failure is discharging a patient with a normal early chest radiograph who later develops blast lung and respiratory failure, or intubating with a delayed “wait and see” approach despite progressive airway edema from inhalational injury.
The Atypical Presentation
The walking wounded may have only tinnitus, abdominal discomfort, mild dyspnea, or a ruptured tympanic membrane, while the dangerous injury evolves over hours. Pulse oximetry can be misleading in carbon monoxide exposure, and early radiographs may be normal in blast lung. Reconstruct the mechanism, examine the ears and chest, obtain serial vitals and lung assessments, and use carboxyhemoglobin testing when CO exposure is plausible.
Back to Our Patient
Back to the 37-year-old construction worker: the enclosed explosion, soot, tachypnea, tinnitus, and multiple casualties create concern for inhalational injury and occult blast trauma even before obvious wounds appear. He is assessed as potentially sick because airway edema and blast lung can evolve; serial chest examinations, carbon monoxide evaluation, and imaging are obtained while trauma resuscitation proceeds. If his voice becomes hoarse or work of breathing increases, early RSI is performed rather than waiting for obstruction; with persistent respiratory symptoms and enclosed-space exposure, he is admitted to a trauma ICU for observation and supportive care.
Patient Presentation to Attending
“This is a 37-year-old man exposed to an enclosed warehouse explosion, now with soot around his mouth, tinnitus, tachypnea, and mild dyspnea but no external penetrating injury. He is awake and protecting his airway, with no stridor, hypotension, unilateral absent breath sounds, hemoptysis, or focal neurologic deficit at present. Because this is an enclosed-space blast, I am concerned for evolving inhalational injury, carbon monoxide exposure, and blast lung despite an initially reassuring saturation. I recommend trauma resuscitation, high-concentration oxygen as clinically indicated, serial airway and respiratory examinations, chest imaging, carboxyhemoglobin testing, and eFAST. He should be observed in a trauma-capable setting, with early intubation if airway edema or respiratory failure develops.”
Study Directive
Draw the primary, secondary, tertiary, and quaternary blast mechanisms from memory and give two examples of each.
Practice a 60-second blast history: distance, enclosure, water, debris, burns, entrapment, and time course.
Review RSI and burn-center criteria, then state your airway threshold for suspected inhalational injury.
Complete five cases involving blast lung, CO poisoning, penetrating injury, and crush syndrome.
Key Medications
Fentanyl 25–50 mcg IV, repeat every 5 minutes and titrate; monitor respiratory depression.
Etomidate 0.3 mg/kg IV for RSI induction; consider lower dosing in profound shock per local protocol.
Rocuronium 1.2 mg/kg IV for RSI paralysis.
Cefazolin 2 g IV for selected open contaminated wounds; broaden based on wound type and local trauma guidance.
TXA 1 g IV over 10 minutes, then 1 g over 8 hours for qualifying traumatic hemorrhage within 3 hours; check protocol when timing or indication is uncertain.
Tetanus vaccine 0.5 mL IM; tetanus immune globulin 250 IU IM when indicated.
Pediatric RSI and antibiotic doses are weight-based; use a pediatric resuscitation reference.
High-Yield Pearls
A ruptured tympanic membrane confirms significant blast exposure but does not predict the absence or presence of blast lung.
Enclosed-space explosions increase concern for inhalational injury and CO exposure; water exposure increases the importance of primary blast effects on hollow organs.
Normal early imaging does not end evaluation when symptoms or mechanism are concerning.
The Mimics
Simple anxiety/hyperventilation — normal oxygenation, lung examination, and serial assessment; mislabeling blast lung delays respiratory support.
Pulmonary contusion — blunt-trauma mechanism and patchy infiltrates without classic pressure-wave exposure; confusing mechanisms can miss ear, bowel, or air-embolism risks.
Carbon monoxide poisoning — headache, confusion, or syncope with potentially normal pulse oximetry; relying on SpO₂ can falsely reassure.
Tension pneumothorax — unilateral absent breath sounds and shock; imaging before decompression can be fatal.
Board Question
After an enclosed-space explosion, a patient is confused but has a pulse oximeter reading of 99% on room air. What is the most important next consideration?
ADischarge because oxygen saturation is normal
BCarbon monoxide exposure and co-oximetry assessment
CImmediate chest tube placement
DProphylactic antibiotics for all blast victims
Reveal answer
Correct: B
Standard pulse oximetry cannot reliably distinguish oxyhemoglobin from carboxyhemoglobin and may appear normal in CO poisoning. Assess exposure history, obtain co-oximetry, and provide oxygen based on clinical context.
Provides an emergency-focused framework for recognizing blast mechanisms, screening for occult pulmonary, auditory, and abdominal injury, and anticipating delayed deterioration.
4 of 4
Hanging and Strangulation Injuries
Strangulation can cause delayed airway edema, laryngeal injury, cervical spine injury, carotid/vertebral artery dissection, cerebral hypoxic injury, and...
0:00 / –:––AI‑generated audio
The Case
A 29-year-old woman is found sitting on the floor of a bedroom, hoarse and frightened, with a narrow red mark circling her neck. She says she briefly lost consciousness but now has a normal oxygen saturation and only mild neck tenderness. Her partner reports that she was suspended for an uncertain length of time and that the event followed an argument. She wants to go home, but the airway and vascular examination are not yet complete.
Before You Read
Which findings demand immediate airway control or advanced imaging?
Does the presence or absence of external marks determine risk?
What disposition and safety evaluation are required even when imaging is normal?
Why It Matters
Strangulation can cause delayed airway edema, laryngeal injury, cervical spine injury, carotid/vertebral artery dissection, cerebral hypoxic injury, and recurrent violence. External findings may be minimal or absent despite life-threatening internal injury.
When to Think of It
Any hanging, ligature strangulation, manual strangulation, or neck compression with dyspnea, dysphonia, odynophagia, neck pain, dysphagia, petechiae, facial or conjunctival hemorrhage, neurologic symptoms, incontinence, loss of consciousness, or amnesia.
Sick or Not Sick
Sick vs. not sick: Is the airway threatened or is there neurologic/vascular injury? Immediate danger signs include stridor, progressive voice change, drooling, respiratory distress, expanding neck swelling, significant tenderness, focal neurologic deficit, seizure, persistent altered mental status, or hemodynamic instability.
The First Fifteen Minutes
Airway edema, stridor, respiratory distress, or inability to protect the airway → early RSI with etomidate 0.3 mg/kg IV and rocuronium 1.2 mg/kg IV, with the most experienced airway operator and surgical-airway backup; edema can make delayed rescue intubation impossible.
Hypoxemia → supplemental oxygen titrated to adequate oxygenation; it corrects hypoxemia but does not treat airway obstruction or vascular injury.
Suspected opioid-associated respiratory depression → naloxone 0.04 mg IV, repeated every 2 minutes and escalated to 0.4 mg, 2 mg, or 4 mg until adequate spontaneous ventilation; titration avoids precipitated withdrawal while reversing hypoventilation. If the exposure is unclear, do not let naloxone delay airway management.
Cervical spine tenderness, neurologic deficit, altered mental status, or concerning mechanism → maintain cervical motion restriction and obtain appropriate CT cervical spine; immobilization limits secondary spinal injury while evaluation proceeds.
Ongoing major hemorrhage from associated trauma → activate massive transfusion and give blood products per local protocol; neck compression itself is usually not treated with empiric blood-thinning medication.
Do not administer corticosteroids or prophylactic antibiotics routinely; they do not prevent the principal complications of strangulation and may distract from airway, vascular, and safety assessment.
Definitive Care & Disposition
Obtain CT angiography of the neck when there is focal neurologic deficit, carotid bruit, significant neck tenderness/swelling, concerning mechanism, near-hanging with symptoms, or other institutional high-risk criteria; consult trauma, vascular, ENT, or neurosurgery for abnormalities. Flexible nasolaryngoscopy evaluates laryngeal injury when the patient is stable and airway-protected. Observe symptomatic patients—especially those with voice change, dysphagia, neck pain, hypoxia, or loss of consciousness—for delayed edema and neurologic deterioration; admit those with airway injury, abnormal imaging, neurologic injury, persistent symptoms, or unsafe disposition. Every case requires suicide-risk assessment when intentional self-harm is possible and screening for intimate-partner violence, with safeguarding and social-work involvement.
How This One Kills
The key failure is discharging a patient with a normal oxygen saturation and minimal bruising who later develops airway obstruction or suffers an untreated carotid dissection; a reassuring surface examination does not exclude deep injury.
The Atypical Presentation
Patients may minimize the event, have no visible ligature mark, or present days later with headache, cognitive change, dysphonia, or dysphagia. Children, older adults, and patients with baseline communication limitations may provide little history. Ask privately and nonjudgmentally about the mechanism, duration, loss of consciousness, voice and swallowing changes, and safety at home; repeat airway and neurologic assessments rather than relying on the initial appearance.
Back to Our Patient
Back to the 29-year-old woman: her transient loss of consciousness, hoarse voice, neck mark, and uncertain suspension make this a symptomatic strangulation injury even though her oxygen saturation is normal. She is kept under close airway observation with cervical precautions, undergoes CT angiography and laryngeal assessment based on symptoms, and is not discharged solely because the external injury is subtle. If imaging and airway evaluation remain normal and symptoms resolve, she still requires a documented safety plan, suicide and violence assessment, reliable supervision, and appropriate follow-up; persistent hoarseness, abnormal imaging, or unsafe housing requires admission.
Patient Presentation to Attending
“This is a 29-year-old woman after an apparent hanging with reported brief loss of consciousness, current hoarseness, and a circumferential neck mark. She is oxygenating normally and protecting her airway, but has mild neck tenderness; she has no stridor, drooling, focal neurologic deficit, seizure, or expanding swelling at this time. The absence of hypoxia or dramatic external injury does not exclude laryngeal edema or blunt cerebrovascular injury. I recommend monitored airway observation, cervical precautions, CT angiography based on her symptoms and mechanism, and ENT evaluation if voice or swallowing symptoms persist. I will also complete suicide-risk and intimate-partner-violence assessments before determining disposition.”
Study Directive
Memorize the red flags for advanced airway management and CTA after strangulation.
Practice a private, trauma-informed strangulation history and document loss of consciousness, incontinence, voice, swallowing, vision, and neurologic symptoms.
Review your institution’s observation and CTA criteria; compare them with current trauma/ENT guidance.
Complete five cases that require different dispositions: discharge with safety planning, observation, ICU airway monitoring, and operative management.
Key Medications
Etomidate 0.3 mg/kg IV for RSI induction; dosing may be adjusted in profound shock per local protocol.
Rocuronium 1.2 mg/kg IV for RSI paralysis.
Naloxone 0.04 mg IV, escalating every 2 minutes to restore ventilation; if apnea is severe, larger initial doses or IM/IN routes may be required. Check institutional opioid-overdose protocol.
Oxygen: titrate by delivery device to clinical oxygenation targets; avoid delaying ventilation or intubation for a saturation number.
No routine steroids, antibiotics, or anticoagulation solely for strangulation; anticoagulation for confirmed blunt cerebrovascular injury requires specialist/trauma guidance.
Pediatric airway and naloxone dosing are weight-based; use a pediatric resuscitation reference.
High-Yield Pearls
No neck mark does not mean no strangulation injury; deep airway and vascular damage can occur without bruising.
Voice change, dysphagia, and neck tenderness are higher-yield danger signals than pulse oximetry alone.
A medically “normal” evaluation does not make the patient safe for discharge without suicide and violence-risk assessment.
The Mimics
Anxiety or panic — symptoms improve with reassurance and there is no dysphonia, dysphagia, tenderness, or neurologic finding; mislabeling strangulation misses evolving airway or vascular injury.
Simple cervical strain — pain without compression history or airway/neurologic signs; missing the mechanism leads to inadequate vascular and safety evaluation.
Opioid intoxication — depressed mental status and hypoventilation with miosis; treating only overdose can miss concurrent hanging trauma.
Seizure/syncope — transient loss of consciousness without neck compression; confusing the sequence can reverse cause and effect and miss intentional violence or hypoxic injury.
Board Question
A patient presents after near-hanging with persistent hoarseness and neck tenderness but normal oxygen saturation and no focal neurologic deficit. Which approach is most appropriate?
ADischarge because the oxygen saturation is normal
BObtain only a plain neck radiograph
CMonitor closely and evaluate for laryngeal and vascular injury
DStart empiric anticoagulation before imaging
Reveal answer
Correct: C
Hoarseness and neck tenderness are red flags for occult laryngeal or vascular injury and delayed airway compromise. Imaging and specialty assessment should guide treatment; empiric anticoagulation is not appropriate before establishing the diagnosis.
Provides clinically relevant data on the diagnostic yield of advanced imaging after near-hanging or strangulation, informing ED decisions about evaluation for occult cervical spine, airway, and vascular injury.
Yesterday’s Differential
The daily puzzle — from editions past
A quick test of recall from prior editions. Commit to an answer before you check.
From yesterday's edition
A 23-year-old man presents with palpitations. His baseline ECG shows a PR interval under 120 ms, a slurred upstroke at the beginning of the QRS, and a mildly widened QRS complex. What’s the diagnosis, and the first move?
Check your answer
Wolff-Parkinson-White. For stable regular SVT, follow local SVT pathway while considering the mechanism. For irregular wide-complex tachycardia suspicious for pre-excited AF, avoid AV nodal blockers, use procainamide if stable, and cardiovert if unstable.
From the August 5 edition
Today, three days ago: Magnesium Sulfate. What’s the adult ED dose, and the contraindication you’d most regret missing?
Check your answer
Torsades: 2 g IV over 1–2 min, may repeat. Severe asthma: 2 g IV over 20 min. Eclampsia: 4–6 g IV load over 15–20 min, then 1–2 g/h infusion. Heart block; myasthenia gravis (relative); severe renal impairment without level monitoring.
From the July 29 edition
A 29-year-old healthy adult has 8 days of cough after rhinorrhea. Temperature is 37.2°C, respiratory rate 16/min, oxygen saturation 99%, and lung examination reveals diffuse rhonchi that clear with cough. Sputum is yellow. What is the best management?
AAmoxicillin-clavulanate
BAzithromycin
CChest radiograph and supportive care
DSupportive care without routine antibiotics
Reveal answer
Correct · D
Acute bronchitis is generally viral; sputum color does not distinguish bacterial infection. Imaging is unnecessary when pneumonia is unlikely based on stable vitals and examination.
Journal Watch
From the FOAMed wire
Notable posts and reviews from the last week, ranked by relevance to today’s lead and source trust.
A 37-year-old African American female presents with persistent dry cough and generalized fatigue that has been worsening over the last two months. She has had some mild dyspnea on exertion but denies any fevers or unexplained weight loss. She has had a few episodes that she...
In this episode, Sam Ashoo, MD and Dr. T.R. Eckler, MD discuss the July 2026 Emergency Medicine Practice article, Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Diagnosis and Management in the Emergency Department . 0:17 – Intro & sponsor promo 1:09 – Episode introduction 4:03 – Definitions: SJS vs. TEN vs. "overlap" by body surface area 6:12 –...
Facial trauma is common in emergency medicine, but the biggest pitfalls are often not the fractures themselves—they're the threatened airway, vision-threatening ocular injuries, missed septal hematomas, and subtle...
Pharmacology Corner
Two drugs for the shift
One antimicrobial and one other ED workhorse — selected daily, with sources and last-reviewed dates so every dose is cross-checkable.
Antimicrobial of the Day
Gentamicin
Aminoglycoside antibiotic
Indication
Severe gram-negative infection adjunct, pyelonephritis/urosepsis in selected regimens, synergy for select endocarditis regimens, and OB/GYN infections per local protocols.
What’s your dose? — reveal dosing & cautions
ED Dose
Extended-interval severe infection: 5–7 mg/kg IV once using adjusted body weight when indicated. Synergy dosing is lower, often 1–1.5 mg/kg IV q8h with levels.
Renal Adjustment
Renally cleared; extend interval and use levels in renal impairment. Avoid repeat dosing without pharmacy guidance when CrCl is low/unknown.
Loop diuretics, vancomycin, amphotericin, cisplatin increase nephro/ototoxicity; neuromuscular blockers may be potentiated.
Monitoring
Creatinine, drug levels for ongoing therapy, hearing/vestibular symptoms, urine output.
ED Pearl
A single ED dose can be powerful gram-negative coverage, but the second dose is where toxicity planning starts — involve pharmacy early if renal function is abnormal.
Trauma with significant hemorrhage within 3 h of injury; postpartum hemorrhage; severe epistaxis; menorrhagia; perioperative bleeding.
What’s your dose? — reveal dosing & cautions
ED Dose
Trauma: 1 g IV over 10 min, then 1 g IV over 8 h (CRASH-2 protocol). Postpartum hemorrhage: 1 g IV over 10 min within 3 h, may repeat once. Topical/nebulized for epistaxis or hemoptysis.
Renal Adjustment
CrCl 50–80: 10 mg/kg q12h (chronic dosing). CrCl < 30: avoid or use markedly reduced dose. Trauma loading dose generally given regardless.
Contraindications
Active intravascular thrombosis or thromboembolic disease; subarachnoid hemorrhage (relative — risk vs benefit); known hypersensitivity.
For educational use only. Verify dosing against the FDA label and your institution’s pharmacy resources before administering.
ECG of the Day
Pulmonary
Right Ventricular Hypertrophy
A dominant R wave in V1 with right axis deviation and right precordial strain is the ECG fingerprint of a pressure-loaded right ventricle.
The Tracing
A 54-year-old woman with longstanding dyspnea on exertion has an ECG done for palpitations. The frontal axis is swung far to the right, around +150 degrees. In V1 the QRS is dominated by a tall R wave over 7 mm with an R/S ratio greater than 1, while V6 shows a correspondingly deep dominant S wave. The right precordial leads V1-4 carry down-sloping ST depression with T wave inversion, and the same strain pattern reaches into the inferior leads. The P wave in lead II is tall and peaked at over 2.5 mm. The QRS is not wide enough to be a bundle branch block. The overall picture is of a right-sided chamber under strain.
Dominant R wave in V1 (> 7 mm tall or R/S ratio > 1)
Dominant S wave in V5 or V6 (> 7 mm deep or R/S ratio < 1)
QRS duration < 120 ms (changes not attributable to RBBB)
Supporting features: right ventricular strain (ST depression / T wave inversion in V1-4 and inferior leads II, III, aVF), P pulmonale, and an S1-S2-S3 pattern
Pearls
A dominant R in V1 has a short, high-stakes differential; pairing it with right axis deviation and a right precordial strain pattern is what points specifically at RVH rather than the other causes of tall R in V1.
Read the supporting cast: P pulmonale (P wave in II > 2.5 mm) signals the right atrial enlargement that so often travels with a pressure-overloaded right ventricle.
The causes are the clinical story — pulmonary hypertension, mitral stenosis, PE, chronic lung disease (cor pulmonale), congenital disease like Tetralogy of Fallot, and ARVC — so let the ECG send you looking for the right-heart process behind it.
Pitfalls
Standard RVH voltage criteria do not apply in the presence of RBBB — there are no universally accepted criteria in that setting, so don't force the diagnosis on a wide QRS.
The right precordial strain pattern (ST depression, T inversion in V1-4) can be misread as anterior ischemia rather than RV strain.
Requiring QRS < 120 ms matters: attributing the tall R in V1 to hypertrophy when it is really a bundle branch block leads to the wrong conclusion.
At the Bedside
Read RVH as a signal to hunt for and manage the underlying right-heart process — pursue evaluation for pulmonary hypertension, PE, valvular or chronic lung disease rather than treating the tracing itself. In the right context (acute dyspnea) new RV strain should raise your suspicion for pulmonary embolism.
For educational use only. Verify ECG interpretation against the LITFL entry and your institution’s practice before clinical decision-making.
Case of the Day
From the lead · Nasal Bone Fractures
Self-Examination
Test Your Understanding
A 19-year-old has nasal trauma with persistent obstruction. Examination shows a soft, fluctuant, bluish swelling of the anterior septum that is tender and does not improve with oxymetazoline. What is the best next step?
ADischarge with oral antibiotics
BCT head without contrast
CUrgent incision and drainage with ENT involvement
DDelayed closed reduction in 10–14 days
Reveal answer
Correct answer · C
A septal hematoma requires prompt drainage to prevent cartilage ischemia, abscess, and saddle-nose deformity. Imaging and delayed reduction do not address the time-sensitive problem.
Study Pace4 topics today; Issue 25 of 94 — Trauma (Weeks 14-15)Deadline · June 1, 2026