An Emergency Medicine Broadsheet
·Phoenix·
Est. MMXXVI
Blue Fish Med · Today's Topic
Malrotation/Midgut Volvulus
Midgut volvulus can infarct the bowel fast; the window to save intestine and life is narrow. Missing it is one of the classic catastrophic pediatric abdominal failures.
A 9-day-old boy is brought in limp and quiet, his diaper stained with a streak of green that catches the overhead light. He had been feeding well until an hour ago, when he suddenly drew up his legs, cried hard, and then went eerily still. His belly is only mildly distended, but the nurse says his heart rate has climbed and he looks “not right.” You place a hand on the warmer and wonder what you can’t afford to miss.
— What’s your move? Read on.
Before you read
What finding makes bilious emesis a surgical emergency until proven otherwise?
What do you do in the first 15 minutes before imaging is even finished?
When to Think of It
Think malrotation/volvulus in any neonate or infant with bilious emesis, sudden irritability or lethargy, abdominal distension, bloody stool, shock, or pain out of proportion to exam. The alarm bell is green vomit in a young child until proven otherwise.
Sick or Not Sick
The fork is stable malrotation vs. ischemic volvulus. If there are signs of shock, peritonitis, hematochezia, metabolic acidosis, or severe persistent pain, treat as volvulus and get surgery immediately.
The First Fifteen Minutes
NPO + immediate pediatric surgery consult — because this may be a surgical bowel ischemia emergency.
IV or IO access, fluid bolus 20 mL/kg isotonic crystalloid; repeat as needed — because perfusion to threatened bowel and shocked child must be restored.
If significant pain/distress: fentanyl 1–2 mcg/kg IV/IN — because analgesia is humane and does not “mask” volvulus.
If ongoing emesis or aspiration risk: ondansetron 0.15 mg/kg IV/PO once (max 8 mg) — because it reduces vomiting while you stabilize and image.
If toxic, febrile, peritoneal, or concern for ischemic bowel/perforation: broad-spectrum antibiotics now such as piperacillin-tazobactam 80 mg/kg/dose piperacillin component IV q6h (max 4.5 g/dose) — because transmural injury can seed bacteremia.
Place NG/OG tube for decompression if distended or actively vomiting — because it lowers aspiration risk and gastric pressure.
Urgent imaging if stable enough: abdominal radiograph and upper GI contrast study are typical diagnostic steps; in an unstable child, do not delay OR for perfect imaging.
Definitive Care & Disposition
Definitive treatment is operative correction (often Ladd procedure) with detorsion if volvulus is present. All suspected volvulus needs admission, and any unstable, peritoneal, or ischemic patient goes directly to the OR; ICU after surgery is common if shock or bowel loss occurred.
How This One Kills
The killer error is sending a bilious-vomiting infant for routine workup or discharge while the bowel twists ischemically. Delay converts salvageable bowel into short-gut syndrome or death.
The Differential — What Else Looks Like This
Gastroenteritis — diarrhea and sick contacts point away; confusing it with volvulus delays surgery and can cost bowel.
Pyloric stenosis — classically nonbilious projectile vomiting in a younger infant; missing volvulus means you ignore a surgical ischemia emergency.
Sepsis/meningitis — lethargy and poor feeding overlap; confusing them can delay decompression and operative management.
Intussusception — episodic pain and currant-jelly stool are clues; confusing it with volvulus can misdirect imaging and operative urgency.
The Second-Day Story
Not every child declares itself with dramatic green emesis. Older infants can present with intermittent pain, feeding refusal, or “reflux” that suddenly worsens; premature or medically complex infants may show only lethargy, tachycardia, or subtle abdominal discoloration. A relatively soft abdomen does not reassure you if the vomiting is bilious or the child looks toxic.
Back to Our Patient
Back to our 9-day-old boy with green emesis and rising heart rate: bilious vomiting in a neonate makes malrotation with midgut volvulus the diagnosis until proven otherwise. He is NPO, resuscitated with a 20 mL/kg isotonic bolus, given fentanyl for distress, decompressed with NG/OG, and the pediatric surgeon is called immediately while imaging is expedited only if it won’t delay the OR. If he has acidosis, peritoneal signs, or instability, he goes straight to operative detorsion and Ladd procedure, then admission to a higher level of care.
Patient Presentation to Attending
How you’d present this patient on the floor — tight, pertinent positives and negatives, no rambling
“This is a 9-day-old male with sudden bilious vomiting and lethargy. He was feeding normally until about an hour ago, then developed green emesis, irritability, and now looks pale and less responsive. No diarrhea, no sick contacts, and no prior abdominal surgery; exam shows mild abdominal distension, tachycardia, and no obvious peritonitis, but he looks ill. I’m worried about malrotation with midgut volvulus causing evolving bowel ischemia. I’ve made him NPO, started IV access and a 20 mL/kg bolus, placed surgery consult stat, and we’re getting an upper GI if it won’t delay definitive management.”
Study Directive
Draw the malrotation/volvulus pathway from memory: embryology error → narrow mesenteric base → volvulus → ischemia.
Practice a 30-second “bilious vomiting in infant” script: recognize, resuscitate, consult surgery, avoid delays.
Review the standard imaging sequence and the circumstances where you skip straight to the OR.
Write down your institution’s pediatric antibiotic and fluid protocols for suspected ischemic bowel.
Necrotizing enterocolitis can progress from subtle feeding intolerance to perforation, shock, and death. Early recognition changes survival, bowel length,...
0:00 / –:––AI‑generated audio
The Case
A 28-week preemie in the NICU rolls from pink to dusky under the glow of the monitors, his belly getting tight and shiny beneath a warmed blanket. The nurse points to a residual that looks coffee-brown, and the diaper has a smear that isn’t reassuring. He is feeding less, breathing a little faster, and the monitor is beginning to complain. Something in his gut has turned dangerous, and the next move matters.
Before You Read
Which premature infant with feeding intolerance needs bowel rest and surgery awareness now?
What signs distinguish NEC from routine prematurity-related belly trouble?
What should happen in the first 15 minutes before the abdomen declares itself?
Why It Matters
Necrotizing enterocolitis can progress from subtle feeding intolerance to perforation, shock, and death. Early recognition changes survival, bowel length, and disposition.
When to Think of It
Think NEC in a premature or very low birth weight infant with feeding intolerance, emesis, abdominal distension, bloody stools, apnea/bradycardia, lethargy, temperature instability, or worsening respiratory status. The classic bedside clue is a preterm infant who “just seems off” plus a distended or tender abdomen.
Sick or Not Sick
The key fork is possible early NEC vs. severe NEC/perforation/shock. Any pneumatosis, portal venous gas, free air, worsening acidosis, thrombocytopenia, or systemic instability means advanced disease and urgent surgical involvement.
Place NG/OG tube for decompression if distended or vomiting — because it decreases intraluminal pressure and aspiration risk.
IV access and isotonic fluid bolus 10–20 mL/kg if poorly perfused — because NEC can progress to septic shock.
Start broad-spectrum antibiotics promptly; common ED choices include ampicillin 50 mg/kg/dose IV q6–8h + gentamicin 4–5 mg/kg IV q24h + metronidazole 7.5 mg/kg IV q8h or an institutional single-agent alternative — because NEC is a bowel-injury/sepsis syndrome.
Get abdominal radiograph urgently — because pneumatosis intestinalis or free air changes management immediately.
If respiratory compromise or apnea: support airway/oxygenation as needed — because systemic illness is often the first sign of gut necrosis.
Early pediatric surgery consult — because perforation or failed medical management may need laparotomy.
Definitive Care & Disposition
Admit all suspected NEC, often to the NICU or PICU depending on stability. Medical NEC gets bowel rest, antibiotics, serial exams, and serial films/labs; surgical NEC needs operative management for perforation, necrosis, or deterioration despite treatment. Parenteral nutrition is typically added later after bowel rest is established.
How This One Kills
The fatal error is treating a preterm infant’s distension and bloody stool as “just feeding intolerance.” Delay allows transmural necrosis, perforation, and septic shock.
The Atypical Presentation
NEC is often sneaky: apnea, bradycardia, increased oxygen needs, temperature instability, or vague “not tolerating feeds” may precede any dramatic abdominal exam. The abdomen can be only mildly distended early, especially in very premature infants, so a benign-looking belly does not clear the diagnosis. Any change in stool color, residual quality, or systemic status in a preterm infant deserves a low threshold for films and surgical awareness.
Back to Our Patient
Back to our 28-week preemie with a tight belly and bloody smear: this is NEC until proven otherwise. He is made NPO, decompressed with NG/OG, resuscitated if perfusion is poor, started on broad-spectrum antibiotics, and gets an urgent abdominal film while the NICU and pediatric surgery teams are notified. If imaging shows pneumatosis or free air, or he worsens clinically, he needs escalation to surgical management and ICU-level care.
Patient Presentation to Attending
“This is a 28-week premature infant with increasing abdominal distension, feeding intolerance, and a bloody stool smear. Over the last few hours he’s had more apnea/bradycardia events and looks more lethargic, but there’s no clear respiratory source. Abdomen is tender and mildly distended, and he’s on enteral feeds. I’m concerned for necrotizing enterocolitis, so I’ve made him NPO, placed NG decompression, started weight-based broad-spectrum antibiotics, and ordered an abdominal radiograph with pediatric surgery and NICU aware.”
Study Directive
Memorize Bell staging at a high level and practice identifying when disease becomes surgical.
Review neonatal abdominal radiographs until pneumatosis and free air are instantly recognizable.
Build a one-minute “preemie with bloody stool” algorithm: NPO, NG, fluids, antibiotics, x-ray, surgery.
Compare NEC vs milk protein intolerance vs Hirschsprung-associated enterocolitis in a flashcard set.
Key Medications
Ampicillin 50 mg/kg/dose IV q6–8h.
Gentamicin 4–5 mg/kg IV q24h.
Metronidazole 7.5 mg/kg IV q8h.
Alternative broad coverage depends on local neonatal protocol; verify with NICU/pharmacy reference.
Normal saline or Lactated Ringer’s 10–20 mL/kg IV bolus if shock/poor perfusion.
High-Yield Pearls
In a preemie, apnea/bradycardia can be the first sign of NEC before the belly looks dramatic.
Pneumatosis intestinalis is a film finding you do not “watch and wait” on in the sick neonate.
Bloody stool in a premature infant is NEC until proven otherwise, especially with distension or systemic instability.
The Mimics
Sepsis — systemic instability overlaps; missing NEC delays bowel rest and imaging.
Milk protein intolerance/allergic proctocolitis — the baby may have blood in stool, but the absence of systemic toxicity and pneumatosis helps; confusing it with NEC can either miss necrosis or overtreat a benign condition.
Hirschsprung-associated enterocolitis — distension and enterocolitis overlap; missing it means you fail to address an obstructive lesion.
Gastroesophageal reflux/feeding intolerance — common in preemies, but unlike NEC it should not cause pneumatosis, bloody stools, or marked systemic decline.
Board Question
A 30-week premature infant develops feeding intolerance, abdominal distension, and a bloody stool. Abdominal x-ray shows pneumatosis intestinalis. What is the best next step?
AResume feeds slowly and repeat exam in 6 hours
BStart bowel rest, broad-spectrum antibiotics, and surgical consultation
CDischarge with close pediatric follow-up
DTreat as milk protein allergy with formula change only
Reveal answer
Correct: B
Pneumatosis intestinalis in a premature infant is highly concerning for NEC and requires immediate bowel rest, antibiotics, and surgical involvement. Delaying treatment risks perforation, sepsis, and death.
A 12-year-old girl sits curled on the stretcher, one hand pressed to the right lower quadrant, the other to her hoodie strings, trying not to cry. She says the pain started near her belly button yesterday and now every step makes it worse. Her mother adds that she threw up once, hasn’t wanted dinner, and “she never acts like this.” The exam is not dramatic, but it is quietly ominous, and you have to decide what this is before it declares itself.
Before You Read
What child with abdominal pain is appendicitis until you prove otherwise?
Which history details matter more than the perfectly normal-looking abdomen?
When is imaging helpful, and when does a surgical consult matter more?
Why It Matters
Appendicitis is common, deceptive, and easy to undercall in children. Delay increases perforation, abscess, length of stay, and complications.
When to Think of It
Think appendicitis in a child with periumbilical pain migrating to the RLQ, anorexia, nausea/vomiting, fever, RLQ tenderness, pain with hopping/walking, guarding, or Rovsing/psoas/obturator signs. Younger children may present vaguely; the diagnosis should enter your head with nearly any focal lower abdominal pain plus anorexia.
Sick or Not Sick
The key fork is uncomplicated vs perforated/complicated appendicitis. Toxic appearance, diffuse peritonitis, persistent tachycardia, high fever, marked leukocytosis, or free fluid/abscess pushes you toward complicated disease and urgent surgery.
The First Fifteen Minutes
NPO + IV access — because surgery and sedation may be coming.
Isotonic fluid bolus 10–20 mL/kg IV if dehydrated or tachycardic — because kids often present volume depleted from vomiting/poor intake.
Analgesia: morphine 0.05–0.1 mg/kg IV or fentanyl 1–2 mcg/kg IV/IN — because pain control does not obscure appendicitis.
Antiemetic: ondansetron 0.15 mg/kg IV/PO once (max 8 mg) if vomiting — because it helps hydration and comfort.
Labs and imaging guided by age/risk: CBC, CRP, UA, pregnancy test when applicable; ultrasound first in most children — because imaging can support but should not delay surgical awareness in high-likelihood cases.
If perforation/sepsis suspected: broad-spectrum antibiotics such as ceftriaxone 50 mg/kg IV q24h + metronidazole 10 mg/kg IV q8h or local equivalent — because source control alone is not enough once contamination occurs.
Definitive Care & Disposition
All confirmed or high-probability appendicitis gets pediatric surgery consultation. Uncomplicated cases often go to appendectomy or selected nonoperative pathways depending on local practice; perforated cases need admission, antibiotics, and possible drainage/operation. Disposition is at least admission for proven appendicitis; sick, perforated, or unable-to-tolerate-PO patients need inpatient care.
How This One Kills
The classic miss is assuming a child with vague abdominal pain and minimal tenderness “doesn’t look surgical.” Perforation can occur after a deceptively mild exam, especially in younger kids.
The Atypical Presentation
Children often do not read the textbook. The pain may be poorly localized, the fever absent, and vomiting may come before pain in younger kids. In adolescents, the key discriminator is often loss of appetite plus movement-related RLQ pain; in younger children, irritability, limp walking, or refusal to jump may be the clue.
Back to Our Patient
Back to our 12-year-old with periumbilical pain that migrated to the RLQ, anorexia, and pain with walking: this is appendicitis until proven otherwise. She is made NPO, given IV fluids and analgesia, and gets ultrasound with early pediatric surgery involvement; if imaging or exam suggests perforation, antibiotics are started and admission is arranged. The disposition is inpatient, not discharge, because children can deteriorate after a deceptively modest exam.
Patient Presentation to Attending
“This is a 12-year-old girl with 24 hours of abdominal pain that started periumbilically and migrated to the right lower quadrant, plus anorexia and one episode of vomiting. She has pain with walking and focal RLQ tenderness, but no diffuse peritonitis; vitals show mild tachycardia and low-grade fever. UA is not suggestive of UTI, and pregnancy testing is negative if applicable. I’m concerned for appendicitis, so she’s NPO, getting IV fluids and analgesia, and I’d like an RLQ ultrasound and pediatric surgery notified.”
Study Directive
Drill the pediatric appendicitis history pattern: anorexia → migration → movement pain → RLQ tenderness.
Practice choosing ultrasound vs CT vs surgery consult in three age-based scenarios.
Memorize your ED antibiotics for perforated appendicitis and the indications for starting them.
Rehearse a one-minute abdominal pain oral presentation focused on discriminating features.
Key Medications
Morphine 0.05–0.1 mg/kg IV.
Fentanyl 1–2 mcg/kg IV/IN.
Ondansetron 0.15 mg/kg IV/PO once (max 8 mg).
Ceftriaxone 50 mg/kg IV q24h if perforation suspected; check local max dose.
Metronidazole 10 mg/kg IV q8h for intra-abdominal anaerobic coverage; verify institutional dosing.
Pediatric antibiotic pathways vary; confirm with your local protocol.
High-Yield Pearls
A child who won’t hop, walk, or jump because of abdominal pain is telling you something important.
Appendicitis may have a bland exam early; progression of symptoms matters more than a single snapshot.
Pain control is appropriate before surgical evaluation; withholding analgesia is outdated and harmful.
The Mimics
Mesenteric adenitis — often post-viral and less focal; confusing it with appendicitis can lead to unnecessary surgery or missed perforation.
Ovarian torsion — sudden unilateral lower abdominal pain in a female child; missing it risks loss of the ovary.
Gastroenteritis — diarrhea and diffuse cramping point away; confusing it with appendicitis delays source control.
Constipation — common and tempting, but focal RLQ tenderness and anorexia should keep appendicitis on the table; missing it delays surgery.
Board Question
A 10-year-old boy has anorexia, periumbilical pain migrating to the RLQ, and pain when hopping. Which finding most strongly supports appendicitis over gastroenteritis?
AWatery diarrhea
BPain worsened by movement
CSick contacts at school
DNausea after eating greasy foods
Reveal answer
Correct: B
Pain that worsens with movement is a classic peritoneal/appendiceal clue and helps distinguish appendicitis from gastroenteritis. Diarrhea and sick contacts point more toward infection, while greasy food triggers are nonspecific.
A 24-year-old man arrives from the alley with a small puncture over the left chest and a shirt that’s turning darker by the second. He is pale, breathing fast, and keeps saying he “can’t catch” his breath while gripping the rail with one hand. The monitor shows a rising pulse and the room has gone very quiet around the wound. You have seconds to decide whether this is just a hole in the skin or a hole in the chest that will kill him.
Before You Read
Which penetrating chest wound is immediately life-threatening even if the skin opening looks small?
What first move distinguishes a manageable chest injury from an arrest-in-waiting?
When do you go from tubes and scans to the OR?
Why It Matters
Penetrating chest trauma can hide tension pneumothorax, massive hemothorax, tamponade, or great-vessel injury behind a tiny wound. Rapid recognition and decisive decompression save lives.
When to Think of It
Any penetrating injury to the chest with dyspnea, hypoxia, tachycardia, hypotension, unilateral absent breath sounds, JVD, tracheal deviation, muffled heart sounds, frothy blood, or ongoing external bleeding should trigger the penetrating thoracic trauma pathway. Small wounds can still mean major internal damage.
Sick or Not Sick
The key fork is hemodynamically stable vs unstable with a thoracic killer until proven otherwise. Unstable patients with signs of tension pneumothorax, massive hemothorax, or tamponade need immediate intervention, not prolonged imaging.
The First Fifteen Minutes
Apply oxygen and monitor continuously — because hypoxemia and decompensation can evolve fast.
If tension pneumothorax suspected: immediate needle or finger decompression, then chest tube; use a large-bore catheter or finger thoracostomy per local protocol — because relieving intrathoracic pressure restores venous return.
If hemothorax suspected or significant chest bleeding: tube thoracostomy, typically 28–36 Fr in adults — because blood must be drained and quantified.
If pericardial tamponade suspected and peri-arrest: immediate resuscitative thoracotomy in the appropriate setting — because it can release tamponade and allow aortic cross-clamp/repair.
If hypotensive from bleeding: activate massive transfusion and give balanced blood products — because crystalloids alone worsen coagulopathy.
Analgesia as needed: fentanyl 25–50 mcg IV titrated carefully in adults — because pain control helps ventilation; avoid over-sedation in unstable patients.
eFAST and chest x-ray only if they do not delay life-saving intervention — because imaging is secondary to stabilization in the crashing patient.
Definitive Care & Disposition
Stable patients need CT angiography/trauma evaluation, chest tube management, and observation/admission. Unstable patients or those with massive hemothorax, ongoing hemorrhage, or tamponade need emergent operative management and trauma surgery involvement; disposition is ICU or OR, not the floor. Ongoing air leak, retained hemothorax, or associated injuries may later require VATS or thoracotomy.
How This One Kills
The deadly miss is assuming a small puncture wound is benign while tension physiology or occult hemorrhage builds. Another classic error is delaying decompression for imaging in an unstable patient.
The Atypical Presentation
Penetrating thoracic trauma does not always look dramatic at the skin. A small entrance wound may hide a large hemothorax, a lung laceration, or pericardial penetration; elderly patients or intoxicated patients may appear deceptively calm until they suddenly crash. If the story and physiology are bad, trust the physiology over the wound size.
Back to Our Patient
Back to our 24-year-old with a small left chest puncture and rapidly worsening dyspnea: this is penetrating thoracic trauma with concern for a life-threatening intrathoracic injury. He gets oxygen, continuous monitoring, and immediate bedside assessment for tension physiology; if unilateral breath sounds are absent or he deteriorates, decompression and chest tube placement happen now, not after CT. If he remains unstable despite decompression or shows tamponade/massive hemothorax, trauma surgery and the OR are activated, with disposition to ICU or operative management.
Patient Presentation to Attending
“This is a 24-year-old man with a penetrating left chest wound and progressive dyspnea, tachycardia, and pallor. The wound is small externally, but he’s breathing fast and looks hemodynamically threatened; I’m concerned about tension pneumothorax, hemothorax, or tamponade. I’ve placed him on oxygen and monitoring, and I’m checking for unilateral breath sounds and signs of shock while preparing for immediate decompression if indicated. If he’s unstable, I want trauma surgery at bedside and a chest tube or thoracotomy pathway ready.”
Study Directive
Rehearse the penetrating chest trauma algorithm: oxygen, monitor, decompress if tension, tube for hemothorax, surgery for tamponade/ongoing hemorrhage.
Practice identifying when imaging is appropriate versus harmful delay.
Review indications for resuscitative thoracotomy and massive transfusion activation.
Drill the difference between simple pneumo, tension pneumo, hemothorax, and tamponade using one-line discriminators.
Key Medications
Fentanyl 25–50 mcg IV titrated in adults for analgesia; use weight-based caution in smaller patients.
Ketamine 0.1–0.3 mg/kg IV for analgesia/sedation in select stable patients; verify local trauma practice if uncertain.
Blood products per massive transfusion protocol; ratios vary by institution.
Local anesthetic for procedure: lidocaine 1% without epinephrine, typical adult max dosing depends on weight/epinephrine status; check reference if uncertain.
Pediatric trauma procedures require weight-based dosing and institutional guidance.
High-Yield Pearls
Wound size does not predict injury severity in penetrating chest trauma.
In unstable trauma, treat physiology first; CT is for the patient who survives to the scanner.
Ongoing external bleeding from the chest can represent major intrathoracic loss, not a “superficial” wound.
The Mimics
Simple pneumothorax — the patient is usually less toxic; confusing it with tension misses the need for immediate decompression.
Cardiac tamponade — JVD, muffled sounds, and shock overlap; missing tamponade can be fatal without surgical rescue.
Pulmonary contusion — hypoxia after trauma may be from contusion, but confusing it with chest wall pain alone can delay tube placement or trauma workup.
Esophageal rupture — chest pain and subcutaneous emphysema can overlap; missing it delays antibiotics and surgical consultation.
Board Question
A stab wound to the chest patient becomes hypotensive with absent breath sounds on the left and severe respiratory distress. What is the best next step?
AObtain a CT chest before treatment
BPerform immediate decompression of the left chest
CGive oral analgesics and observe
DDischarge if the wound is small
Reveal answer
Correct: B
This is tension pneumothorax until proven otherwise, and immediate decompression is life-saving. Imaging must not delay treatment in an unstable patient.
A quick test of recall from prior editions. Commit to an answer before you check.
From yesterday's edition
A 51-year-old woman with sudden dyspnea, pleuritic chest pain, and syncope has an ECG showing sinus tachycardia, a new right bundle branch block, right-axis deviation, and deep T-wave inversions in V1 through V4 and lead III. The classic S1Q3T3 pattern is present but subtle. What’s the diagnosis, and the first move?
Check your answer
Pulmonary Embolism / RV Strain. Use the ECG to support concern for RV strain and severity while pursuing PE workup. If unstable, activate local massive PE pathway, obtain bedside echo when available, start anticoagulation if not contraindicated, and consider thrombolysis or advanced therapy per protocol.
From the June 10 edition
Today, three days ago: Glucagon. What’s the adult ED dose, and the contraindication you’d most regret missing?
Check your answer
Hypoglycemia: 1 mg IM/SC/IN. Beta-blocker overdose: 3–10 mg IV bolus, then infusion at effective bolus dose per hour; give antiemetic due vomiting risk. Pheochromocytoma, insulinoma/glucagonoma caution; hypersensitivity.
From the June 3 edition
A 68-year-old woman arrives with dizziness, hypotension, and a heart rate of 32/min. ECG shows complete heart block with a wide QRS escape rhythm. After atropine 1 mg IV, there is no improvement. What is the best next step?
ARepeat atropine until a total of 10 mg is given
BTranscutaneous pacing and prepare for transvenous pacing
CAdenosine 6 mg IV
DAmiodarone 150 mg IV
Reveal answer
Correct · B
Transcutaneous pacing and prepare for transvenous pacing. Atropine often fails in infranodal block and wide-complex escape rhythms, especially with hemodynamic instability. The priority is immediate pacing support while arranging definitive temporary pacing and treating reversible causes.
Journal Watch
From the FOAMed wire
Notable posts and reviews from the last week, ranked by relevance to today’s lead and source trust.
Vrinda Chenthil Kumar and Mike Cadogan Foreign body pulmonary embolisation Case review of Implanon NXT migration to the pulmonary artery: missing implant, subtle CXR clue, CTPA diagnosis and endovascular retrieval.
A 45-year old African American woman presents with progressive fatigue over the past week and has experienced intermittent episodes of severe hand pain that typically self-resolve. She has also noted a worsening headache over the last day. Her blood pressure is 197/105 mm Hg...
In this episode, Sam Ashoo, MD and Dr. T.R. Eckler, MD discuss the April 2026 Emergency Medicine Practice article, Wide Complex Tachycardia in the Emergency Department: An Updated Approach to Diagnosis and Management . Introduction – 0:11 Article Overview – 2:02 Top 5 Bedside Steps – 7:54 Sodium Channel Blockade – 9:26 Hyperkalemia – 11:53 SVT with...
This week we have pieces on thalamic strokes from Evie and Swami, updates on the recent AHA peds life support guidelines from Ilene, and a big two-parter on hyponatremia with none other than George Willis. 1....
Pharmacology Corner
Two drugs for the shift
One antibiotic and one other ED workhorse — selected daily, with sources and last-reviewed dates so every dose is cross-checkable.
Antibiotic of the Day
Acyclovir
Guanosine analog antiviral
Indication
Suspected HSV encephalitis, severe disseminated HSV/VZV, varicella complications, and immunocompromised herpesvirus infection.
What’s your dose? — reveal dosing & cautions
ED Dose
HSV encephalitis: 10 mg/kg IV q8h using ideal or adjusted body weight per local protocol. Severe VZV often 10 mg/kg IV q8h. Give with IV fluids unless contraindicated.
Renal Adjustment
Renally cleared; reduce interval/dose for CrCl <50 mL/min. Ensure hydration to reduce crystal nephropathy.
Contraindications
Acyclovir hypersensitivity. Use caution with renal impairment, dehydration, and concurrent nephrotoxins.
Interactions
Nephrotoxins increase AKI risk; probenecid may increase acyclovir levels.
Monitoring
Creatinine, urine output, neurotoxicity in renal dysfunction, IV site irritation.
ED Pearl
In possible HSV encephalitis, acyclovir is like antibiotics for meningitis — do not wait for LP if imaging/LP logistics are delaying treatment.
Procedural sedation, RSI induction (especially in shock), analgesia (sub-dissociative dosing), agitated delirium / excited delirium, refractory status asthmaticus.
What’s your dose? — reveal dosing & cautions
ED Dose
RSI induction: 1.5–2 mg/kg IV. Procedural sedation: 1–2 mg/kg IV or 4–5 mg/kg IM. Sub-dissociative analgesia: 0.1–0.3 mg/kg IV (or 0.5 mg/kg IN). Excited delirium: 4–5 mg/kg IM.
Renal Adjustment
No specific renal adjustment.
Contraindications
Schizophrenia (relative — risk of psychotic decompensation); known hypersensitivity. Historic contraindication of elevated ICP is largely refuted; use with hemodynamic awareness.
Continuous SpO2 + ETCO2 during dissociative dosing; cardiac monitor; have airway equipment at bedside (laryngospasm is rare but possible).
ED Pearl
Dose-dependent personality: at 0.1–0.3 mg/kg it's an opioid-sparing analgesic with minimal dissociation; at ≥1 mg/kg it's a full dissociative — dose error here is the main source of bad ED experiences with ketamine.
For educational use only. Verify dosing against the FDA label and your institution’s pharmacy resources before administering.
ECG of the Day
Ischemia
Right Ventricular STEMI
RV infarction makes the patient preload-dependent; V4R ST elevation changes your nitrate and fluid decisions.
The Tracing
A 64-year-old man with inferior STEMI becomes hypotensive after a small dose of nitroglycerin. His lungs are clear and JVP is elevated. Right-sided ECG leads show ST elevation in V4R. The cath lab is already being activated, but the resuscitation plan changes immediately.
Usually occurs with inferior STEMI, especially proximal RCA occlusion
ST elevation in V4R is the most useful right-sided lead finding
May show ST elevation in V1 with inferior STEMI
Clinical triad can include hypotension, clear lungs, and elevated JVP
May be associated with bradycardia or high-grade AV block
Pearls
Any hypotensive inferior STEMI deserves right-sided leads.
RV infarct patients may need cautious fluids to maintain preload while awaiting reperfusion.
Clear lungs in a hypotensive STEMI patient are a clue that the shock may be RV/preload physiology rather than left-sided pulmonary edema.
Pitfalls
Do not give nitrates reflexively to inferior STEMI with hypotension or suspected RV involvement.
Absence of classic JVP findings does not exclude RV infarct in a chaotic ED exam.
RV infarct and PE can both create right-sided strain; the inferior STEMI pattern points you to the culprit.
At the Bedside
Activate STEMI pathway, avoid nitrates if RV infarct suspected, give cautious IV fluids if hypotensive without pulmonary edema, treat bradyarrhythmias, and expedite reperfusion.
For educational use only. Verify ECG interpretation against the LITFL entry and your institution’s practice before clinical decision-making.
Case of the Day
From the lead · Malrotation/Midgut Volvulus
Self-Examination
Test Your Understanding
A 2-week-old neonate has abrupt bilious vomiting and intermittent crying. Abdomen is mildly distended, cap refill is prolonged, and lactate is elevated. What is the most appropriate next step?
AReassure the parents and discharge with close follow-up
BStart oral rehydration and schedule outpatient ultrasound
CImmediate pediatric surgery consultation and resuscitation with IV fluids
DGive broad-spectrum antibiotics only and observe in the ED
Reveal answer
Correct answer · C
Bilious vomiting in a neonate is bowel obstruction until proven otherwise, and malrotation with volvulus can rapidly progress to ischemia. Immediate resuscitation and surgical involvement are the priority; imaging should not delay definitive management if the child is unstable.
Study Pace4 topics today; 124 remaining; Day 12 of 43Deadline · June 1, 2026